Randomized Phase III Trial of Adjuvant Chemotherapy with S-1 after Curative Treatment in Patients with Squamous-Cell Carcinoma of the Head and Neck (ACTS-HNC)

@inproceedings{Tsukahara2015RandomizedPI,
  title={Randomized Phase III Trial of Adjuvant Chemotherapy with S-1 after Curative Treatment in Patients with Squamous-Cell Carcinoma of the Head and Neck (ACTS-HNC)},
  author={Kiyoaki Tsukahara and Akira Kubota and Yasuhisa Hasegawa and Hideki Takemura and Tomonori Terada and Takahide Taguchi and Kunihiko Nagahara and Hiroaki Nakatani and Kunitoshi Yoshino and Yuichiro Higaki and Shigemichi Iwae and Takeshi Beppu and Yutaka Hanamure and Kichinobu Tomita and Naoyuki Kohno and Kazuyoshi Kawabata and Masanori Fukushima and Satoshi Teramukai and Masato Fujii},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND We conducted a phase III study to evaluate S-1 as compared with UFT as control in patients after curative therapy for stage III, IVA, or IVB squamous-cell carcinoma of the head and neck (SCCHN). PATIENTS AND METHODS Patients were randomly assigned to the UFT group (300 or 400 mg day-1 for 1 year) or the S-1 group (80, 100, or 120 mg day-1 for 1 year). The primary end point was disease-free survival (DFS). Secondary end points were relapse-free survival, overall survival (OS), and… CONTINUE READING
Tweets
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 25 REFERENCES

Maintenance Chemotherapy With UFT for Head and Neck Carcinoma

  • M Tsukuda, H Miyake
  • ONCOLOGY
  • 2000
Highly Influential
13 Excerpts

Similar Papers

Loading similar papers…