Randomized Manipulation of Early Cognitive Experience Impacts Adult Brain Structure

@article{Farah2021RandomizedMO,
  title={Randomized Manipulation of Early Cognitive Experience Impacts Adult Brain Structure},
  author={Martha J. Farah and Saul Sternberg and Thomas A. Nichols and Jeffrey T. Duda and Terry Lohrenz and Yi Luo and Libbie Sonnier and Sharon L. Ramey and P. Read Montague and Craig T. Ramey},
  journal={Journal of Cognitive Neuroscience},
  year={2021},
  volume={33},
  pages={1197-1209}
}
Abstract Does early exposure to cognitive and linguistic stimulation impact brain structure? Or do genetic predispositions account for the co-occurrence of certain neuroanatomical phenotypes and a tendency to engage children in cognitively stimulating activities? Low socioeconomic status infants were randomized to either 5 years of cognitively and linguistically stimulating center-based care or a comparison condition. The intervention resulted in large and statistically significant changes in… Expand
Human brain anatomy reflects separable genetic and environmental components of socioeconomic status
TLDR
A well-powered voxel-based analysis of grey matter volume across levels of SES finds many small SES effects widely distributed across the brain, including cortical, subcortical and cerebellar regions, which affects multiple brain regions through measurable genetic and environmental effects. Expand
Association between Neighborhood Socioeconomic Status and Executive System Activation in Youth
TLDR
Higher neighborhood SES was associated with greater activation of the executive system to WM load, including the bilateral dorsolateral prefrontal cortex, posterior parietal cortex, and precuneus, and associations remained significant when controlling for related factors like parental education and exposure to traumatic events. Expand
Sex differences in the effects on the brain of early cognitive stimulation.
A study by Farah and colleagues (2021) of the effects on the adult brain of a cognitively intense early childhood experience revealed large effects, but primarily in the brains of male subjects,Expand

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