Randomized Clinical Trial: Macrogol/PEG 3350 Plus Electrolytes for Treatment of Patients With Constipation Associated With Irritable Bowel Syndrome

@article{Chapman2013RandomizedCT,
  title={Randomized Clinical Trial: Macrogol/PEG 3350 Plus Electrolytes for Treatment of Patients With Constipation Associated With Irritable Bowel Syndrome},
  author={Roger W. Chapman and Vincenzo Stanghellini and Mike Geraint and Marc Halphen},
  journal={The American Journal of Gastroenterology},
  year={2013},
  volume={108},
  pages={1508-1515}
}
OBJECTIVES:Polyethylene glycol (PEG) 3350 plus electrolytes (PEG 3350+E) is an established treatment for constipation and has been proposed as a treatment option for constipation associated with irritable bowel syndrome (IBS–C). This study aimed to compare the efficacy and safety of PEG 3350+E vs. placebo in adult patients with IBS–C.METHODS:Following a 14-day run-in period without study medication, patients with confirmed IBS–C were randomized to receive PEG 3350+E (N=68) or placebo (N=71) for… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Similar Papers

Loading similar papers…