Randomized, placebo-controlled, double-blind trial of Swedish snus for smoking reduction and cessation

BACKGROUND Epidemiological studies suggest that smokeless tobacco in the form of Swedish snus has been used by many smokers in Scandinavia to quit smoking, but the efficacy of snus has so far not been evaluated in controlled clinical trials. METHODS We conducted a randomized, double-blind, placebo-controlled, clinical trial aimed at assessing the efficacy… (More)