Randomized, placebo‐controlled trial of incobotulinumtoxina for upper‐limb post‐stroke spasticity

@inproceedings{Elovic2016RandomizedPT,
  title={Randomized, placebo‐controlled trial of incobotulinumtoxina for upper‐limb post‐stroke spasticity},
  author={Elie Paul Elovic and Michael C. Munin and Petr Kaňovsk{\'y} and Angelika Hanschmann and Reinhard Hiersemenzel and Christina Marciniak},
  booktitle={Muscle & nerve},
  year={2016}
}
INTRODUCTION Efficacy and safety of incobotulinumtoxinA in post-stroke upper-limb spasticity were studied. METHODS Subjects randomized 2:1 to incobotulinumtoxinA (fixed dose 400 U) or placebo, with fixed doses for the primary target clinical pattern (PTCP; flexed elbow, 200 U; flexed wrist, 150 U; clenched fist, 100 U). Doses for non-primary patterns were flexible within predefined ranges. RESULTS At week 4, incobotulinumtoxinA led to larger improvements in PTCP Ashworth scale (AS) scores… CONTINUE READING
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References

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Showing 1-10 of 30 references

Efficacy and safety of botulinum neurotoxin NT 201 in poststroke upper-limb spasticity

  • P Kanovsk y, J Slawek, Z Denes, T Platz, I Sassin, G Comes
  • Clin Neuropharmacol
  • 2009
Highly Influential
6 Excerpts

Efficacy and safety of treatment with incobotulinum toxin A (botulinum neurotoxin type A free from complexing proteins; NT 201) in poststroke upper-limb spasticity

  • P Kanovsk y, J Slawek, Z Denes, T Platz, G Comes, S Grafe
  • J Rehabil Med
  • 2011
Highly Influential
4 Excerpts

Botox R US prescribing information. Available at http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103000s5 232lbl.pdf

  • Allergan, Inc
  • Last updated 2013. Accessed December
  • 2014
3 Excerpts

Dysport R US prescribing information. Available at http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/ 125274s0052lbl.pdf

  • Ipsen Biopharm, Ltd
  • Last updated 2009. Accessed December
  • 2014

Xeomin R US prescribing information. Available at http://www.xeomin.com/consumers/pdf/xeomin-fullprescribing-information.pdf

  • Merz Pharmaceuticals, Ltd
  • Last updated 2014. Accessed December
  • 2014

IncobotulinumtoxinA demonstrated therapeutic equivalence to onabotulinumtoxinA in the treatment of blepharospasm and cervical dystonia

  • R Benecke, P Roggenk€amper, D. Hauschke
  • J Neurol Sci
  • 2013

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