Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation.

@article{Wingard2010RandomizedDT,
  title={Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation.},
  author={John R Wingard and Shelly L Carter and Thomas J Walsh and Joanne Kurtzberg and Trudy N. Small and Lindsey Robert Baden and Iris D Gersten and Adam M. Mendizabal and Helen L. Leather and Dennis L. Confer and Richard T Maziarz and Edward A. Stadtmauer and Javier Bola{\~n}os-Meade and Janice M. Y. Brown and John F. DiPersio and Michael Boeckh and Kieren a. Marr},
  journal={Blood},
  year={2010},
  volume={116 24},
  pages={5111-8}
}
Invasive fungal infection (IFI) is a serious threat after allogeneic hematopoietic cell transplant (HCT). This multicenter, randomized, double-blind trial compared fluconazole (N = 295) versus voriconazole (N = 305) for the prevention of IFI in the context of a structured fungal screening program. Patients undergoing myeloablative allogeneic HCT were randomized before HCT to receive study drugs for 100 days, or for 180 days in higher-risk patients. Serum galactomannan was assayed twice weekly… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 31 references

Factors associated with overall and attributable mortality in invasive aspergillosis

Y Nivoix, M Nelton, V Letscher-Bru
Clin Infect Dis • 2008

Hallucinations during voriconazole therapy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2008

Numbers needed to treat with posaconazole prophylaxis to prevent invasive fungal infection and death.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2008

Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2008

Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo sign.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2007
View 1 Excerpt

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