Randomized, double-blind comparison of immediate-release omeprazole oral suspension versus intravenous cimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients.

@article{Conrad2005RandomizedDC,
  title={Randomized, double-blind comparison of immediate-release omeprazole oral suspension versus intravenous cimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients.},
  author={Steven A. Conrad and Andrea Gabrielli and Benjamin A Margolis and Andrew Quartin and J Steven Hata and William O Frank and Robert G Bagin and James A Rock and Bonnie Hepburn and Loren Laine},
  journal={Critical care medicine},
  year={2005},
  volume={33 4},
  pages={760-5}
}
OBJECTIVE To demonstrate that a new immediate-release omeprazole oral suspension is effective in preventing upper gastrointestinal bleeding in critically ill patients. DESIGN A noninferiority analysis was used to compare rates of clinically significant upper gastrointestinal bleeding in a prospective, phase 3, double-blind trial with parallel omeprazole suspension and cimetidine treatment groups. SETTING A total of 47 intensive care units in the United States. PATIENTS A total of 359… CONTINUE READING
44 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 44 extracted citations

Similar Papers

Loading similar papers…