Randomized, double-blind, placebo-controlled clinical trial for evaluating the efficacy of fractional CO2 laser compared with topical estriol in the treatment of vaginal atrophy in postmenopausal women

@article{Cruz2018RandomizedDP,
  title={Randomized, double-blind, placebo-controlled clinical trial for evaluating the efficacy of fractional CO2 laser compared with topical estriol in the treatment of vaginal atrophy in postmenopausal women},
  author={V. L. Cruz and M. L. Steiner and L. Pompei and R. Strufaldi and F. Fonseca and Lucila H. Simardi Santiago and Tali Wajsfeld and C. Fernandes},
  journal={Menopause},
  year={2018},
  volume={25},
  pages={21–28}
}
Objective: The aim of the study was to evaluate efficacy of fractional CO2 vaginal laser treatment (Laser, L) and compare it to local estrogen therapy (Estriol, E) and the combination of both treatments (Laser + Estriol, LE) in the treatment of vulvovaginal atrophy (VVA). [...] Key Method Methods: A total of 45 postmenopausal women meeting inclusion criteria were randomized in L, E, or LE groups.Expand
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