Randomized, double-blind, placebo-controlled clinical trial for evaluating the efficacy of fractional CO2 laser compared with topical estriol in the treatment of vaginal atrophy in postmenopausal women
@article{Cruz2018RandomizedDP, title={Randomized, double-blind, placebo-controlled clinical trial for evaluating the efficacy of fractional CO2 laser compared with topical estriol in the treatment of vaginal atrophy in postmenopausal women}, author={V. L. Cruz and M. L. Steiner and L. Pompei and R. Strufaldi and F. A. Fonseca and L. Santiago and Tali Wajsfeld and C. E. Fernandes}, journal={Menopause}, year={2018}, volume={25}, pages={21–28} }
Objective: The aim of the study was to evaluate efficacy of fractional CO2 vaginal laser treatment (Laser, L) and compare it to local estrogen therapy (Estriol, E) and the combination of both treatments (Laser + Estriol, LE) in the treatment of vulvovaginal atrophy (VVA). [...] Key Method Methods: A total of 45 postmenopausal women meeting inclusion criteria were randomized in L, E, or LE groups.Expand Abstract
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References
SHOWING 1-10 OF 32 REFERENCES
A 12-week treatment with fractional CO2 laser for vulvovaginal atrophy: a pilot study
- Medicine
- Climacteric : the journal of the International Menopause Society
- 2014
- 190
- PDF
An assessment of the safety and efficacy of a fractional CO2 laser system for the treatment of vulvovaginal atrophy
- Medicine
- Menopause
- 2016
- 80
- PDF
Use of a novel fractional CO2 laser for the treatment of genitourinary syndrome of menopause: 1-year outcomes
- Medicine
- Menopause
- 2017
- 50
- PDF
Microablative fractional CO2-laser therapy and the genitourinary syndrome of menopause: An observational study.
- Medicine
- Maturitas
- 2016
- 54
- PDF
Sexual function after fractional microablative CO2 laser in women with vulvovaginal atrophy
- Medicine
- 2015
- 104
- PDF
Vulvar and vaginal atrophy in postmenopausal women: findings from the REVIVE (REal Women's VIews of Treatment Options for Menopausal Vaginal ChangEs) survey.
- Medicine
- The journal of sexual medicine
- 2013
- 272
The effect of microablative fractional CO2 laser on vaginal flora of postmenopausal women
- Medicine
- Climacteric : the journal of the International Menopause Society
- 2016
- 58
- PDF