Randomization in the Canadian National Breast Screening Study: a review for evidence of subversion.

@article{Bailar1997RandomizationIT,
  title={Randomization in the Canadian National Breast Screening Study: a review for evidence of subversion.},
  author={John C. Bailar and Brian Macmahon},
  journal={CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year={1997},
  volume={156 2},
  pages={193-9}
}
The authors assess the randomization strategy that had been used in the Canadian National Breast Screening Study (NBSS). Document experts at a private investigation and security company were hired to assist in reviewing instances in which names of subjects were altered in the "allocation books" (the basic instrument used to assign, at random, participants to either the mammography or the usual-care arm). The review was restricted to records from 3 NBSS centres where women assigned to the… CONTINUE READING