Randomised trial of lymphoblastoid α-interferon in chronic hepatitis C: Effects on inflammation, fibrogenesis and viremia

@article{Camps1993RandomisedTO,
  title={Randomised trial of lymphoblastoid α-interferon in chronic hepatitis C: Effects on inflammation, fibrogenesis and viremia},
  author={Jordi Camps and Alberto Castilla and Juan Luis Ruiz and Mar{\'i}a Pilar Civeira and Jes{\'u}s Prieto},
  journal={Journal of hepatology},
  year={1993},
  volume={17 3},
  pages={390-6}
}
Seventy-two patients with chronic hepatitis C were included in a randomised trial of lymphoblastoid interferon versus no treatment. Thirty-six patients entered each group. Interferon was given in a step-down schedule for 12 months. Aminotransferase activities became normal during treatment in 30 of 36 (83.3%) treated patients, but in only 1 out of 36 (2.7%) non-treated cases (p < 0.001). However, a reactivation of the disease during the interferon course was observed in 12 patients after a mean… CONTINUE READING

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