Randomised trial of intravenous immunoglobulin as prophylaxis against infection in plateau-phase multiple myeloma. The UK Group for Immunoglobulin Replacement Therapy in Multiple Myeloma.

@article{Chapel1994RandomisedTO,
  title={Randomised trial of intravenous immunoglobulin as prophylaxis against infection in plateau-phase multiple myeloma. The UK Group for Immunoglobulin Replacement Therapy in Multiple Myeloma.},
  author={Helen M. Chapel and M. Lee and Ruth Hargreaves and Derwood H Pamphilon and Archibald Grant Prentice},
  journal={Lancet},
  year={1994},
  volume={343 8905},
  pages={1059-63}
}
Patients with plateau-phase multiple myeloma have an increased risk of life-threatening bacterial infections and polyclonal humoral immune suppression. We conducted a randomised, double-blind, placebo-controlled, multicentre trial of intravenous immunoglobulin (IVIg) as prophylaxis against infection. 82 patients with stable multiple myeloma received monthly… CONTINUE READING