Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

@article{Group1994RandomisedTO,
  title={Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)},
  author={Scandinavian Simvastatin Survival Study Group},
  journal={The Lancet},
  year={1994},
  volume={344},
  pages={1383-1389}
}
  • Scandinavian Simvastatin Survival Study Group
  • Published 1994
  • Medicine
  • The Lancet
  • Drug therapy for hypercholesterolaemia has remained controversial mainly because of insufficient clinical trial evidence for improved survival. The present trial was designed to evaluate the effect of cholesterol lowering with simvastatin on mortality and morbidity in patients with coronary heart disease (CHD). 4444 patients with angina pectoris or previous myocardial infarction and serum cholesterol 5.5-8.0 mmol/L on a lipid-lowering diet were randomised to double-blind treatment with… CONTINUE READING

    Paper Mentions

    OBSERVATIONAL CLINICAL TRIAL
    The Fast-MI registry was designed to evaluate the "real world" management of patients with acute myocardial infarction (MI), and to assess their in-hospital, medium and long-term… Expand
    ConditionsAcute Myocardial Infarction
    InterventionOther

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 2,906 CITATIONS, ESTIMATED 61% COVERAGE

    FILTER CITATIONS BY YEAR

    1995
    2020

    CITATION STATISTICS

    • 26 Highly Influenced Citations

    • Averaged 78 Citations per year from 2018 through 2020

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 36 REFERENCES