Randomised study of risk of fetal loss related to early amniocentesis versus chorionic villus sampling

@article{Sundberg1997RandomisedSO,
  title={Randomised study of risk of fetal loss related to early amniocentesis versus chorionic villus sampling},
  author={K. Sundberg and J. Bang and S. Smidt‐Jensen and V. Brocks and C. Lundsteen and J. Parner and N. Keiding and J. Philip},
  journal={The Lancet},
  year={1997},
  volume={350},
  pages={697-703}
}
BACKGROUND Several cohort studies have shown the feasibility of early amniocentesis (between 11 and 13 weeks of gestation) as an alternative to chorionic villus sampling (CVS) for karyotyping, but the only completed randomised study of fetal safety showed a significant fetal-loss risk related to first-trimester amniocentesis. We assessed fetal safety in early amniocentesis and CVS. METHODS We assessed early amniocentesis at 11-13 weeks gestational age compared with the fetal risk associated… Expand
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