Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis

@article{Mathie2014RandomisedPT,
  title={Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis},
  author={Robert T. Mathie and Suzanne Lloyd and Lynn Legg and J{\"u}rgen Clausen and Sian Moss and Jonathan R. T. Davidson and Ian Ford},
  journal={Systematic Reviews},
  year={2014},
  volume={3}
}
BackgroundA rigorous and focused systematic review and meta-analysis of randomised controlled trials (RCTs) of individualised homeopathic treatment has not previously been undertaken. We tested the hypothesis that the outcome of an individualised homeopathic treatment approach using homeopathic medicines is distinguishable from that of placebos.MethodsThe review’s methods, including literature search strategy, data extraction, assessment of risk of bias and statistical analysis, were strictly… 
Randomised, double-blind, placebo-controlled trials of non-individualised homeopathic treatment: systematic review and meta-analysis
TLDR
A meta-analysis of all extractable data leads to rejection of the null hypothesis that the main outcome of treatment using a non-individualised (standardised) homeopathic medicine is indistinguishable from that of placebo, but analysis of a small sub-group of reliable evidence does not support that rejection.
Veterinary homeopathy: meta-analysis of randomised placebo-controlled trials.
  • R. Mathie, J. Clausen
  • Medicine, Psychology
    Homeopathy : the journal of the Faculty of Homeopathy
  • 2015
Systematic Review and Meta-Analysis of Randomised, Other-than-Placebo Controlled, Trials of Individualised Homeopathic Treatment.
TLDR
Current data preclude a decisive conclusion about the comparative effectiveness of IHT, but future OTP-controlled trials in homeopathy should aim, as far as possible, to promote both internal validity and external validity.
Veterinary homeopathy: systematic review of medical conditions studied by randomised placebo-controlled trials
TLDR
Mixed findings from the only two placebo-controlled RCTs that had suitably reliable evidence precluded generalisable conclusions about the efficacy of any particular homeopathic medicine or the impact of individualised homeopathic intervention on any given medical condition in animals.
Systematic Review and Meta-Analysis of Randomised, Other-than-Placebo Controlled, Trials of Non-Individualised Homeopathic Treatment.
TLDR
The current data preclude a decisive conclusion about the comparative effectiveness ofNIHT, and the highest intrinsic quality was observed in the equivalence and non-inferiority trials of NIHT.
Veterinary homeopathy: Systematic review of medical conditions studied by randomised trials controlled by other than placebo
TLDR
OTP-controlled trials of veterinary homeopathy do not currently provide useful insight into the effectiveness of homeopathy in animals due to the poor reliability of their data.
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TLDR
Based on the available evidences of the highest level it is not possible to assert that the effects of homeopathic are exclusively placebo effect, and specific effects were detected in several studies.
Homeopathy for Allergic Rhinitis: A Systematic Review.
TLDR
The low or uncertain overall quality of the evidence warrants caution in drawing firm conclusions about intervention effects and use of either Galphimia glauca or a homeopathic nasal spray may have small beneficial effects on the nasal and ocular symptoms of AR.
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