Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis

@article{Elliott1994RandomisedDC,
  title={Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor $\alpha$ (cA2) versus placebo in rheumatoid arthritis},
  author={Michael J. Elliott and Ravinda Nath Maini and Marc Feldmann and Joachim Robert Kalden and C E Antoni and J. S. Smolen and B. Leeb and Ferry C Breedveld and J. D. Macfarlane and J. A. Bijl and James N. Woody},
  journal={The Lancet},
  year={1994},
  volume={344},
  pages={1105-1110}
}
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References

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Preliminary results support the hypothesis that TNF alpha is an important regulator in RA, and suggest that it may be a useful new therapeutic target in this disease.
Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis
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