Randomised controlled trials: subgroup analyses

@article{Sedgwick2014RandomisedCT,
  title={Randomised controlled trials: subgroup analyses},
  author={Philip M. Sedgwick},
  journal={BMJ},
  year={2014},
  volume={349},
  pages={
          g7513
        }
}
The effectiveness of wound edge protection devices in reducing surgical site infection after abdominal surgery was investigated. A randomised controlled trial was undertaken. The intervention was standard intraoperative care plus use of a wound edge protection device during the intra-abdominal part of the operation. The control was standard intraoperative care alone. The sample size for the trial was based on having 80% power to detect a 50% reduction in the infection rate, assuming a rate of… CONTINUE READING
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