Randomised controlled trial of two brief interventions against long-term benzodiazepine use: outcome of intervention

@article{Heather2004RandomisedCT,
  title={Randomised controlled trial of two brief interventions against long-term benzodiazepine use: outcome of intervention},
  author={Nick Heather and Alison J. Bowie and Heather Ashton and Brian R. Mcavoy and I Spencer and Jennifer Brodie and David R. Giddings},
  journal={Addiction Research \& Theory},
  year={2004},
  volume={12},
  pages={141 - 154}
}
Previous studies have reported that a letter from the patient's General Practitioner (GP) and a short GP consultation led to reduced intake among long-term benzodiazepine (BZD) users, with no evidence of a deterioration in general or mental health. We aimed to replicate these earlier findings in a single, prospective RCT and compare the effectiveness of the two brief interventions. 273 long-term BZD users (≥6 mos) identified from repeat prescription computer records of 7 general practices were… Expand
Randomised controlled trial of two brief interventions against long-term benzodiazepine use: Cost-effectiveness
TLDR
The letter was the more cost-effective intervention when taking into account changes in health service use and savings to the drugs bill, and Savings to the District Health Authority would be a minimum of £4.9 million per annum. Expand
Predictors of response to brief intervention in general practice against long-term benzodiazepine use
TLDR
Patients receiving prescriptions from their usual GP are more likely to cease or reduce BZD intake than those receiving medications from another medical practitioner, and general medical practitioners should consider recording the patient's stage of change and tailoring their intervention on that basis. Expand
Minimal interventions to decrease long-term use of benzodiazepines in primary care: a systematic review and meta-analysis.
TLDR
A brief intervention in the form of either a letter or a single consultation by GPs, for long-term users of BZD, is an effective and efficient strategy to decrease or stop their medication, without causing adverse consequences. Expand
Comparative efficacy of two interventions to discontinue long-term benzodiazepine use: cluster randomised controlled trial in primary care
TLDR
A structured intervention with a written individualised stepped-dose reduction is less time-consuming and as effective in primary care as a more complex intervention involving follow-up visits and led to significant reductions in long-term benzodiazepine use in patients without severe comorbidity. Expand
Efficacy of two interventions on the discontinuation of benzodiazepines in long-term users: 36-month follow-up of a cluster randomised trial in primary care.
  • C. Vicens, E. Sempere, +9 authors A. Leiva
  • Medicine
  • The British journal of general practice : the journal of the Royal College of General Practitioners
  • 2016
TLDR
The interventions were effective on cessation of BZD use; most patients who discontinued at 12 months remained abstinent at 3 years and no significant differences in anxiety, depression, or sleep dissatisfaction were shown. Expand
Randomized controlled trial of a brief intervention for problematic prescription drug use in non-treatment-seeking patients.
TLDR
Brief intervention based on Motivational Interviewing is effective in reducing PD intake in non-treatment-seeking patients. Expand
Brief interventions targeting long‐term benzodiazepine and Z‐drug use in primary care: a systematic review and meta‐analysis
TLDR
Brief interventions delivered in primary care are more effective than usual care in reducing and discontinuing long‐term benzodiazepine/Z‐drug use. Expand
Effectiveness of current treatment approaches for benzodiazepine discontinuation: a meta-analysis.
TLDR
Providing an intervention is more effective than routine care and psychological interventions may improve discontinuation above GDR alone, and while some substitutive pharmacotherapies may have promise, current evidence is insufficient to support their use. Expand
Representations Concerning Long-Term Use of Benzodiazepines Hypnotics, by Patients Over 65, Treated in General Practice. A Qualitative Study Using Individual Interviews
TLDR
Withdrawal must take into account the psychological dependence and fragility of elderly patients, and the GP, with his knowledge of the patient’s environment, could take a central role in prudent initiation and in directed withdrawal when this is necessary. Expand
Brief intervention in general hospital for problematic prescription drug use: 12-month outcome.
TLDR
More intensive interventions, booster-sessions or regular aftercare might help in stabilizing intervention effects on PD use among hospital patients, however, studies using larger samples are needed to allow more powerful and specific analyses. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 19 REFERENCES
Controlled evaluation of brief intervention by general practitioners to reduce chronic use of benzodiazepines.
  • K. Bashir, M. King, M. Ashworth
  • Medicine
  • The British journal of general practice : the journal of the Royal College of General Practitioners
  • 1994
TLDR
The study indicates that some chronic users can successfully reduce their intake of benzodiazepines with simple advice from the general practitioner and a self-help booklet and this type of intervention does not lead to psychological distress or increased consultation. Expand
Evaluation of an easy, cost-effective strategy for cutting benzodiazepine use in general practice.
TLDR
It is indicated that a simple intervention can have a considerable effect on the use of hypnotic and anxiolytic drugs, even with a sample of elderly users. Expand
Extent and appropriateness of benzodiazepine use. Results from an elderly urban community.
TLDR
Many older people still use benzodiazepines, contrary to official guidelines with regard to their mental health, adding to the weight of opinion that persistent and long-term use should be discouraged. Expand
Guidelines for the rational use of benzodiazepines. When and what to use.
TLDR
Indications for benzodiazepines include acute stress reactions, episodic anxiety, fluctuations in generalised anxiety, and as initial treatment for severe panic and agoraphobia, and occasionally in acute psychoses. Expand
Cognitive impairment in long-term benzodiazepine users.
TLDR
It was found that patients taking high doses of benzodiazepines for long periods of time perform poorly on tasks involving visual-spatial ability and sustained attention, consistent with deficits in posterior cortical cognitive function. Expand
Next-day memory impairment with triazolam use
TLDR
Cognitive impairments associated with triazolam probably represent a spectrum of organic brain dysfunction, with memory impairment/amnesia and confusion being the commonest, and milder manifestations and hallucinations and delusions the more severe and less common, features. Expand
Tranquillisers: prevalence, predictors and possible consequences. Data from a large United Kingdom survey.
TLDR
Increased probability of current use of tranquilliser/hypnotic use was significantly related to female sex, older age, increased symptoms of psychological malaise and physical ill-health, elevated neuroticism scores on the Eysenck Personality Inventory, lower socioeconomic status, unemployment, current smoking in some groups, and less participation in active leisure pursuits. Expand
Identification of underprivileged areas
TLDR
There are clear indications for health education since there may be groups of women needing vaccination programmes specifically directed at them, and this might well necessitate special programmes in areas where the Asian population is concentrated. Expand
How many subjects? Statistical power analysis in research
TLDR
This stylishly slim volume presents the authors' method of sample size estimation for a wide variety of statistical procedures, along with much useful instruction and many insights into general experimental design. Expand
Evaluation of an easy, costeffective strategy for cutting benzodiazepine use in general practice
  • British Journal of General Practice
  • 1994
...
1
2
...