Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial. Scottish Cancer Trials Breast Group.

@article{Forrest1996RandomisedCT,
  title={Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial. Scottish Cancer Trials Breast Group.},
  author={A. P. M. Forrest and Helen J S Stewart and Dawn Everington and Robin J. Prescott and C S Mcardle and Adrian N. Harnett and David Cameron-5 Smith and William D George},
  journal={Lancet},
  year={1996},
  volume={348 9029},
  pages={708-13}
}
BACKGROUND To determine whether, when primary breast cancer is treated by local excision supported by systemic therapy appropriate to the oestrogen receptor status (ER) of the tumour, local radiotherapy can be avoided. METHODS We carried out a randomised controlled trial in 585 patients aged less than 70 years with primary breast cancers of 4 cm or less in size in four specialist units and seven other hospitals in Scotland. After local excision of the tumour (1 cm margin) and an axillary… CONTINUE READING
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