Randomised clinical trial: the effects of daikenchuto, TU-100, on gastrointestinal and colonic transit, anorectal and bowel function in female patients with functional constipation.

@article{Iturrino2013RandomisedCT,
  title={Randomised clinical trial: the effects of daikenchuto, TU-100, on gastrointestinal and colonic transit, anorectal and bowel function in female patients with functional constipation.},
  author={Johanna Iturrino and Michael Camilleri and Banny S. Wong and Sara J Linker Nord and Duane D. Burton and Alan R. Zinsmeister},
  journal={Alimentary pharmacology & therapeutics},
  year={2013},
  volume={37 8},
  pages={776-85}
}
BACKGROUND Daikenchuto, a Japanese herbal medicine used for post-operative ileus and constipation, dose dependently stimulates gastrointestinal (GI) motility and decreases rectal compliance and sensation. Effects of TU-100 (commercial form of daikenchuto) in adults with constipation are unknown. AIM To compare the effects of oral TU-100, 2.5 g t.d.s. or 5 g t.d.s. and placebo t.d.s. on GI and colonic transit (CT), rectal compliance (RC) and sensation thresholds (RST), anal sphincter pressures… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Herbal Medicines

Methods in Pharmacology and Toxicology • 2016

Constipation and herbal medicine

Front. Pharmacol. • 2015
View 1 Excerpt

Colorectal sensation and motility.

Current opinion in gastroenterology • 2014
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Comparison of calculations to estimate gastric emptying half-time of solids in humans.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2012
View 1 Excerpt

Effect of daikenchuto (TU-100) on gastrointestinal and colonic transit in humans.

American journal of physiology. Gastrointestinal and liver physiology • 2010
View 2 Excerpts

Lower functional gastrointestinal disorders: evidence of abnormal colonic transit in a 287 patient cohort.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2010

Performance characteristics of scintigraphic colon transit measurement in health and irritable bowel syndrome and relationship to bowel functions.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2010
View 2 Excerpts

Scintigraphic biomarkers for colonic dysmotility.

Clinical pharmacology and therapeutics • 2010

Similar Papers

Loading similar papers…