Randomised Clinical Efficacy Trial of Topiramate and Nitrazepam in Treatment of Infantile Spasms


OBJECTIVE Infantile spasms (IS) are among the most catastrophic epileptic syndromes of infancy. The purpose of this study was to compare efficacy and safety of topiramate (TPM) and nitrazepam (NZP) as first-line drugs in the treatment of IS. MATERIALS & METHODS In a parallel single-blinded randomized clinical trial, 50 patients with IS referred to… (More)


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