Randomisation to protect against selection bias in healthcare trials.

  title={Randomisation to protect against selection bias in healthcare trials.},
  author={Jan Odgaard-Jensen and Gunn Elisabeth Vist and Antje Timmer and Regina Kunz and Elie A. Akl and Holger Sch{\"u}nemann and Matthias Briel and Alain J. Nordmann and Silvia Pregno and Andrew D. Oxman},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Randomised trials use the play of chance to assign participants to comparison groups. The unpredictability of the process, if not subverted, should prevent systematic differences between comparison groups (selection bias). Differences due to chance will still occur and these are minimised by randomising a sufficiently large number of people. OBJECTIVES To assess the effects of randomisation and concealment of allocation on the results of healthcare studies. SEARCH STRATEGY We… CONTINUE READING
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