Random stimulation of spider mechanosensory neurons reveals long-lasting excitation by GABA and muscimol.

@article{Pfeiffer2009RandomSO,
  title={Random stimulation of spider mechanosensory neurons reveals long-lasting excitation by GABA and muscimol.},
  author={Keram Pfeiffer and Izabela Panek and Ulli H{\"o}ger and Andrew S. French and P{\"a}ivi H. Torkkeli},
  journal={Journal of neurophysiology},
  year={2009},
  volume={101 1},
  pages={
          54-66
        }
}
gamma-Aminobutyric acid type A (GABA(A)) receptor activation inhibits many primary afferent neurons by depolarization and increased membrane conductance. Deterministic (step and sinusoidal) functions are commonly used as stimuli to test such inhibition. We found that when the VS-3 mechanosensory neurons innervating the spider lyriform slit-sense organ were stimulated by randomly varying white-noise mechanical or electrical signals, their responses to GABA(A) receptor agonists were more complex… 

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