Random number generation during sleep deprivation: effects of caffeine on response maintenance and stereotypy

@article{Gottselig2006RandomNG,
  title={Random number generation during sleep deprivation: effects of caffeine on response maintenance and stereotypy},
  author={Julie Marie Gottselig and Martin Adam and Julia V. R{\'e}tey and Ramin Khatami and Peter Achermann and Hans-Peter Landolt},
  journal={Journal of Sleep Research},
  year={2006},
  volume={15}
}
Neurophysiological and functional imaging studies have demonstrated that frontal regions of the brain are particularly responsive to homeostatic sleep pressure. Previous neuropsychological studies indicate that sleep deprivation causes impairments in prefrontal cortical function. Random number generation (RNG) is thought to provide a sensitive index of executive functions that rely on the prefrontal cortex. The present study tested the hypothesis that sleep deprivation would impair RNG and that… 
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