Random acrocentric bivalent associations in human pachytene spermatocytes. Molecular implications in the occurrence of Robertsonian translocations.

@article{Guichaoua1986RandomAB,
  title={Random acrocentric bivalent associations in human pachytene spermatocytes. Molecular implications in the occurrence of Robertsonian translocations.},
  author={Marie Roberte Guichaoua and Monique Devictor and Mich{\`e}le Hartung and J. M. Luciani and Andr{\'e} Stahl},
  journal={Cytogenetics and cell genetics},
  year={1986},
  volume={42 4},
  pages={191-7}
}
Acrocentric bivalent associations were studied in 232 human male germ cells at pachytene in order to understand better the preferential involvement of chromosomes 13, 14, and 21 in Robertsonian translocations. The tendency of each acrocentric bivalent to associate with another was not correlated with NOR activity, as measured by silver staining. Good agreement was noticed between their ability to associate and the amount of satellite DNA in human acrocentric chromosomes. The distribution of two… CONTINUE READING