Ran on tracks--cytoplasmic roles for a nuclear regulator.

@article{Yudin2009RanOT,
  title={Ran on tracks--cytoplasmic roles for a nuclear regulator.},
  author={Dmitry Yudin and Mike Fainzilber},
  journal={Journal of cell science},
  year={2009},
  volume={122 Pt 5},
  pages={587-93}
}
The GTPase Ran is best known for its crucial roles in the regulation of nucleocytoplasmic transport in interphase cells and in the organization of the spindle apparatus during mitosis. A flurry of recent reports has now implicated Ran in diverse cytoplasmic events, including trafficking of an ephrin receptor homolog in nematode oocytes, control of neurite outgrowth in Drosophila and mammalian neurons, and retrograde signaling in nerve axons after injury. Striking findings suggest that the… CONTINUE READING

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