Raman spectroscopy of bladder tissue in the presence of 5-aminolevulinic acid.

@article{Grimbergen2009RamanSO,
  title={Raman spectroscopy of bladder tissue in the presence of 5-aminolevulinic acid.},
  author={Matthijs C. M. Grimbergen and Christiaan F P van Swol and R Jeroen A van Moorselaar and Jamie Uff and Anita Mahadevan-Jansen and Nicholas Stone},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={2009},
  volume={95 3},
  pages={
          170-6
        }
}
Raman spectroscopy has the ability to provide differential diagnosis of different cancers with high sensitivity and specificity. A major limitation in its clinical application is the weak nature of Raman signal, which inhibits scanning large surface areas of tissues. In bladder cancer diagnosis, fluorescence-guided endoscopy with 5-aminolevulinic acid (5-ALA) has gained interest as a technique that can provide such spatial differentiation, thus improving early detection and more complete… CONTINUE READING
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