Raman spectral imaging of single cancer cells: probing the impact of sample fixation methods

@article{Draux2010RamanSI,
  title={Raman spectral imaging of single cancer cells: probing the impact of sample fixation methods},
  author={Florence Draux and Cyril Gobinet and Josep Sul{\'e}-Suso and Aur{\'e}lie Trussardi and Michel Manfait and Pierre Jeannesson and G. D. Sockalingum},
  journal={Analytical and Bioanalytical Chemistry},
  year={2010},
  volume={397},
  pages={2727-2737}
}
AbstractRaman spectroscopy has proven its potential for the analysis of cell constituents and processes. However, sample preparation methods compatible with clinical practice must be implemented for collection of accurate spectral information. This study aims at assessing, using micro-Raman imaging, the effects of some routinely used fixation methods such as formalin-fixation, formalin-fixation/air drying, cytocentrifugation, and air drying on intracellular spectral information. Data were… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Label-Free Raman Imaging to Monitor Breast Tumor Signatures

  • Technology in cancer research & treatment
  • 2017
VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED