Raltegravir Cerebrospinal Fluid Concentrations in HIV-1 Infection

Abstract

INTRODUCTION Raltegravir is an HIV-1 integrase inhibitor currently used in treatment-experienced HIV-1-infected patients resistant to other drug classes. In order to assess its central nervous system penetration, we measured raltegravir concentrations in cerebrospinal fluid (CSF) and plasma in subjects receiving antiretroviral treatment regimens containing… (More)
DOI: 10.1371/journal.pone.0006877

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