RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program

Abstract

Cancer stem cells evade apoptotic death by blebbishield emergency program, which constructs blebbishields from apoptotic bodies and drives cellular transformation. Von Hippel–Lindau (VHL) plays both tumor suppressor and oncogenic roles, and the reason behind is poorly understood. Here we demonstrate that dimers and trimers of p19-VHL interact with RalBP1 to… (More)
DOI: 10.1038/cddiscovery.2017.23

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@inproceedings{Jinesh2017RalBP1AP, title={RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program}, author={Goodwin G Jinesh and Ashish Madhav Kamat}, booktitle={Cell Death Discovery}, year={2017} }