• Medicine
• Published in
  Journal of neurology…
  1975
• DOI:10.1136/jnnp.38.11.1076

Raised intracranial pressure and cerebral blood flow. 5. Effects of episodic intracranial pressure waves in primates.

@article{Johnston1975RaisedIP,
  title={Raised intracranial pressure and cerebral blood flow. 5. Effects of episodic intracranial pressure waves in primates.},
  author={Ian H. Johnston and John O. Rowan and Deric Minwoo Park and Michael John Rennie},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1975},
  volume={38 11},
  pages={
          1076-82
        }
}

• Ian H. Johnston, John O. Rowan, +1 author Michael John Rennie

The effects of episodic waves of intracranial pressure on cerebral blood flow were studied in primates. Six pressure waves each of 20 minutes' duration and ranging from 50 to 100 mmHg in magnitude were induced in baboons, at intervals of 30 minutes, in an attempt to simulate clinical plateau waves. With pressure waves up to 75 mmHg, cerebral blood flow remained at control levels despite falling cerebral perfusion pressures. Between the initial pressure waves a marked hyperaemia developed, with… CONTINUE READING

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