Raised concentrations of platelet activating factor in colonic mucosa of Crohn's disease patients.

  title={Raised concentrations of platelet activating factor in colonic mucosa of Crohn's disease patients.},
  author={Iradj Sobhani and S Hochlaf and Yves Denizot and Christiane Vissuzaine and E D Ren{\'e} and Jacques Benveniste and Miguel J. M. Lewin and Michel Mignon},
  volume={33 9},
Platelet activating factor (PAF-ACETHER or PAF) and precursors of platelet activating factor were investigated in 26 patients with acute Crohn's disease and in 10 healthy controls. Platelet activating factor, lyso platelet activating factor, and alkyl acyl glycerophosphocholine, were determined in colonic mucosal biopsies in patients with acute Crohn's disease, during prednisolone therapy, and in remission. Biopsy specimens were submitted to histopathology examination and to phospholipid… CONTINUE READING


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