Rainbow trout (Oncorhynchus mykiss) possess two hormone-sensitive lipase-encoding mRNAs that are differentially expressed and independently regulated by nutritional state.

@article{Kittilson2011RainbowT,
  title={Rainbow trout (Oncorhynchus mykiss) possess two hormone-sensitive lipase-encoding mRNAs that are differentially expressed and independently regulated by nutritional state.},
  author={Jeffrey D. Kittilson and Katie M. Reindl and Mark A. Sheridan},
  journal={Comparative biochemistry and physiology. Part A, Molecular & integrative physiology},
  year={2011},
  volume={158 1},
  pages={52-60}
}
Teleost fish store lipids among several tissues primarily as triacylglycerol (TG). Upon metabolic demand, stored TGs are hydrolyzed by hormone-sensitive lipase (HSL). In this study, two distinct cDNAs encoding HSL were isolated, cloned, and sequenced from adipose tissue of rainbow trout. The full-length cDNAs, designated HSL1 and HSL2, were 2562-bp and 2887-bp in length, respectively, and share 82% nucleotide identity. Phylogenetic analysis suggests that the two HSLs derive from paralogous… CONTINUE READING
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