Raft.1, A Monoclonal Antibody Raised Against the Raft Microdomain, Recognizes G-Protein β1 and 2, Which Assemble Near Nucleus After Shiga Toxin Binding to Human Renal Cell Line

Abstract

Raft microdomains are glycolipid-enriched microdomain scaffolding molecules involved in signal transduction. The binding of Shiga toxin to globotriaosyl ceramide in raft microdomains of the human renal tubular cell line ACHN causes temporal activation of Src-kinase Yes. To study the downstream signaling mechanism proceeding to the activation of Yes, we… (More)
DOI: 10.1097/01.LAB.0000044134.23951.C8

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@article{Katagiri2002Raft1AM, title={Raft.1, A Monoclonal Antibody Raised Against the Raft Microdomain, Recognizes G-Protein β1 and 2, Which Assemble Near Nucleus After Shiga Toxin Binding to Human Renal Cell Line}, author={Yohko U. Katagiri and Kazuhiro Ohmi and Weiran Tang and Hisami Takenouchi and Tomoko Taguchi and Nobutaka Kiyokawa and Junichiro Fujimoto}, journal={Laboratory Investigation}, year={2002}, volume={82}, pages={1735-1745} }