Radiotherapy versus single-dose carboplatin in adjuvant treatment of stage I seminoma: a randomised trial

@article{Oliver2005RadiotherapyVS,
  title={Radiotherapy versus single-dose carboplatin in adjuvant treatment of stage I seminoma: a randomised trial},
  author={R Oliver and M. Mason and G Mead and Hans von der Maase and G Rustin and J Joffe and R. F. E. de Wit and Nina Aass and J E Graham and Rob Coleman and Susan Kirk and S Stenning},
  journal={The Lancet},
  year={2005},
  volume={366},
  pages={293-300}
}
BACKGROUND Adjuvant radiotherapy is effective treatment for stage I seminoma, but is associated with a risk of late non-germ-cell cancer and cardiovascular events. After good results in initial studies with one injection of carboplatin, we undertook a large randomised trial to compare the approaches of radiotherapy with chemotherapy in seminoma treatment. METHODS Between 1996 and 2001, 1477 patients from 70 hospitals in 14 countries were randomly assigned to receive radiotherapy (para-aortic… CONTINUE READING

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