Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.

@article{Bonner2006RadiotherapyPC,
  title={Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.},
  author={James A Bonner and Paul M. Harari and Jordi Giralt and Nozar Azarnia and Dong M. Shin and Roger B. Cohen and Christopher U. Jones and Ranjan K. Sur and David Raben and Jacek Jassem and Roger Ove and Merrill S. Kies and Jos{\'e} Baselga and Hagop Youssoufian and Nadia Amellal and Eric Keith Rowinsky and Kian K. Ang},
  journal={The New England journal of medicine},
  year={2006},
  volume={354 6},
  pages={
          567-78
        }
}
BACKGROUND We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal growth factor receptor, in the treatment of locoregionally advanced squamous-cell carcinoma of the head and neck. [] Key MethodMETHODS Patients with locoregionally advanced head and neck cancer were randomly assigned to treatment with high-dose radiotherapy alone (213 patients) or high-dose radiotherapy plus weekly cetuximab (211 patients) at…

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