Radiotherapy enhancement with gold nanoparticles.

@article{Hainfeld2008RadiotherapyEW,
  title={Radiotherapy enhancement with gold nanoparticles.},
  author={James F. Hainfeld and Farrokh Avraham Dilmanian and Daniel N. Slatkin and Henry M. Smilowitz},
  journal={The Journal of pharmacy and pharmacology},
  year={2008},
  volume={60 8},
  pages={
          977-85
        }
}
  • James F. Hainfeld, Farrokh Avraham Dilmanian, +1 author Henry M. Smilowitz
  • Published 2008
  • Medicine, Chemistry
  • The Journal of pharmacy and pharmacology
  • Gold is an excellent absorber of X-rays. If tumours could be loaded with gold, this would lead to a higher dose to the cancerous tissue compared with the dose received by normal tissue during a radiotherapy treatment. Calculations indicate that this dose enhancement can be significant, even 200% or greater. In this paper, the physical and biological parameters affecting this enhancement are discussed. Gold nanoparticles have shown therapeutic efficacy in animal trials and these results are… CONTINUE READING

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