Radiosynthesis of 3-indolyl[1-¹¹C]acetic acid for phyto-PET-imaging: an improved production procedure and formulation method.

@article{Xu2014RadiosynthesisO3,
  title={Radiosynthesis of 3-indolyl[1-¹¹C]acetic acid for phyto-PET-imaging: an improved production procedure and formulation method.},
  author={Youwen Xu and David L. Alexoff and Anna Theresa Kunert and Wenchao Qu and Dohyun Kim and Max Paven and Benjamin A. Babst and Richard A Ferrieri and Michael J. Schueller and Joanna S. Fowler},
  journal={Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine},
  year={2014},
  volume={91},
  pages={155-60}
}
An improved production procedure and formulation method for the carbon-11 radiolabeled phytohormone, 3-indolyl-[l-(11)C]acetic acid ([(11)C]IAA), was developed by modifying selected original reaction parameters. This updated procedure both doubled the yield (from 25.9±6.7% (n=12) to 61.0±0.3% (n=10)) and increased the concentration (0.2-0.4 GBq/0.15-0.3 mL… CONTINUE READING