Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase.

Abstract

INTRODUCTION Developing positron emission tomography (PET) radiotracers for non-invasive study of the cholinergic system is crucial to the understanding of neurodegenerative diseases. Although several acetylcholinesterase (AChE) PET tracers radiolabeled with carbon-11 exist, no fluorinated radiotracer is currently used in clinical imaging studies. The… (More)
DOI: 10.1016/j.nucmedbio.2013.02.004

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Cite this paper

@article{Branquinho2013RadiosynthesisAI, title={Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase.}, author={Emilie Da Costa Branquinho and Guillaume Becker and C{\'e}dric Bouteiller and Ludovic Jean and Pierre-Yves Renard and Luc Zimmer}, journal={Nuclear medicine and biology}, year={2013}, volume={40 4}, pages={554-60} }