Radioreceptor assays for sensitive detection and quantitation of saxitoxin and its analogues from strains of the freshwater cyanobacterium, Anabaena circinalis.

@article{Llewellyn2001RadioreceptorAF,
  title={Radioreceptor assays for sensitive detection and quantitation of saxitoxin and its analogues from strains of the freshwater cyanobacterium, Anabaena circinalis.},
  author={Lyndon E. Llewellyn and Andrew P Negri and Joshua D. Doyle and Phillip D. Baker and Edna Carolina Pinilla Beltran and Brett A Neilan},
  journal={Environmental science & technology},
  year={2001},
  volume={35 7},
  pages={
          1445-51
        }
}
Toxic freshwater cyanobacteria can contaminate water supplies and adversely effect humans, agricultural livestock, and wildlife. Toxicity is strain-specific so morphological observations alone cannot predict the hazard level. Two microtiter plate based bioassays have emerged for measuring saxitoxin (STX) and its derivatives, commonly found in the freshwater cyanobacteria Anabaena and Aphanizomenon. They use radioactively labeled STX binding by sodium channels, STX's pharmacological target, or… CONTINUE READING

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