Radioprotection of plasmid and cellular DNA and Swiss mice by silibinin.


The radioprotective effect of a non-toxic bioactive component in plant milk thistle, silibinin against genotoxicity induced by gamma-irradiation was investigated in vivo/in vitro. Under in vitro conditions of irradiation, silibinin protected plasmid pBR322 DNA against gamma-radiation-induced strand breaks in a concentration dependent manner (0-200microM… (More)
DOI: 10.1016/j.mrgentox.2009.11.007


  • Presentations referencing similar topics