Radionuclide Therapy for Neuroendocrine Tumors.

  title={Radionuclide Therapy for Neuroendocrine Tumors.},
  author={Mauro Cives and Jonathan R. Strosberg},
  journal={Current oncology reports},
  volume={19 2},
Peptide receptor radionuclide therapy (PRRT) is a form of systemic radiotherapy that allows targeted delivery of radionuclides to tumor cells expressing high levels of somatostatin receptors. The two radiopeptides most commonly used for PRRT, 90Y-DOTATOC and 177Lu-DOTATATE, have been successfully employed for more than a decade for the treatment of advanced neuroendocrine tumors (NETs). Recently, the phase III, randomized NETTER-1 trial has compared 177Lu-DOTATATE versus high-dose octreotide… CONTINUE READING
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