Radiolysis and radioracemization of 20 amino acids from the beginning of the Solar System

  title={Radiolysis and radioracemization of 20 amino acids from the beginning of the Solar System},
  author={Franco Cataldo and Ornella Ursini and Giancarlo Angelini and Susana Iglesias-Groth and Arturo Manchado},
  journal={Rendiconti Lincei},
A series of chiral amino acids in the levo form used in the current terrestrial biochemistry were irradiated in the solid and dry state with γ-radiation to a dose of 3.2 MGy which is the dose equivalent to that derived by radionuclide decay in comets and asteroids in 1.05 × 109 years at a depth >20 m. For each amino acids, the radiolysis degree and the radioracemization degree was measured, respectively by differential scanning calorimetry (DSC) and by optical rotatory dispersion (ORD… 

Stability toward High Energy Radiation of Non-Proteinogenic Amino Acids: Implications for the Origins of Life

It is concluded that it is unsurprising to find amino acids even in enantiomeric excess in carbonaceous chondrites.

Radiolysis and radioracemization of RNA ribonucleosides: implications for the origins of life

  • F. Cataldo
  • Physics, Chemistry
    Journal of Radioanalytical and Nuclear Chemistry
  • 2018
The RNA nucleosides, namely adenosine, cytidine, guanosine and uridine were γ-radioyzed in solid state and in vacuo at room temperature to a total dose of 3.2 MGy. Through electronic absorption

Solid state radiolysis of non-proteinaceous amino acids in vacuum: astrochemical implications

The analysis of the amino acids present in Murchison meteorite and in other carbonaceous chondrites has revealed the presence of 66 different amino acids. Only eight of these 66 amino acids are

Radiation chemical aspects of the origins of life

A review is presented on the abiotic synthesis of amino acids and purine and pyrimidine bases in processes involving the action of high energy radiation. It is shown that all the 20 proteinogenic

Mass spectrometric analysis of selected radiolyzed amino acids in an astrochemical context

A selection of amino acids, namely arginine, proline and tyrosine previously irradiated to 3.2 mega-Gray in the solid state and analyzed by differential scanning calorimetry (DSC) and optical

Integrated Molar Absorptivity of Mid- and Far-Infrared Spectra of Glycine and Other Selected Amino Acids.

With the reported values of ɛ and ψ, it will be possible to estimate the relative abundance of these molecules in space environments.

Enrichment of Non-Terrestrial L-Proteinogenic Amino Acids by Aqueous Alteration on the Tagish Lake Meteorite Parent Body

The distribution and isotopic and enantiomeric compositions of amino acids found in three distinct fragments of the Tagish Lake C2-type carbonaceous chondrite were investigated via liquid

High-energy ionizing radiation influence on the fragmentation of glutamine

Abstract Both experimentally, by using the mass-spectrometric technique, and theoretically, by applying Becke’s three-parameter hybrid density functional approach, the yield of the ionic products of

The importance of glyceraldehyde radiolysis in chemical evolution

This work irradiated dl-glyceraldehyde at different doses and temperatures with a gamma source; even at low doses and temperature (77 K), free radicals were detected and among the products formed were ethylene glycol and glycolaldehyde.



Amino acids in comets and meteorites: stability under gamma radiation and preservation of the enantiomeric excess

This study adds experimental support to the suggestion that amino acids were formed in the interstellar medium and in chiral excess and then were incorporated into comets and asteroids at the epoch of Solar system formation.

The radioracemization of amino acids by ionizing radiation: Geochemical and cosmochemical implications

A number of optically active amino acids, both in the solid state and as sodium or hydrochloride salts in aqueous solution, have been exposed to ionizing radiation from a 3000 Ci60Co γ-ray source to

Solid state radiolysis of sulphur-containing amino acids: cysteine, cystine and methionine

The sulphur-containing proteinaceous amino acids l-cysteine, l-cystine and l-methionine were irradiated in the solid state to a dose of 3.2 MGy. This dose corresponds to that delivered by

A detailed analysis of the properties of radiolyzed proteinaceous amino acids

The thermal behaviour of 21 proteinaceous l-amino acids either as pristine samples and also as radiolyzed (3.2 MGy) samples was studied with the differential scanning calorimeter. The onset and peak

Radiation-induced racemization and amplification of chirality: implications for comets and meteorites

  • F. Cataldo
  • Physics
    International Journal of Astrobiology
  • 2007
The action of high-energy radiation on prebiotic chiral molecules plays against the preservation of chirality. Chiral molecules incorporated in comets and meteorites are bombarded for billions of

Racemization of Meteoritic Amino Acids

It is shown that amino acids in meteorites do not necessarily undergo complete racemization by the time they are recovered on Earth, and if the mechanism of amino acid formation imposes some enantiomeric preference on the amino acids, a chiral signature can be retained through the entire history of the meteorite.

Radiogenic heating of comets by 26Al and implications for their time of formation.

It was shown that the influence of the short-lived radionuclide 26Al dominates the effect of other radioactive species for bodies of radii up to approximately 50 km, and an upper limit for the formation time of comets is obtained.

Gamma-radiolysis of chiral terpenes: α-(−)pinene and α-(+)pinene

The terpenes α-(+)-pinene, and α-(−)pinene have been radiolyzed at radiation doses of 150, 300 and 600 kGy. The radiolyzed samples have been analyzed by FT-IR spectroscopy and polarimetry. Both