Radiolabeling of [18F]altanserin - a microfluidic approach.

@article{Ungersbck2012RadiolabelingO,
  title={Radiolabeling of [18F]altanserin - a microfluidic approach.},
  author={Johanna Ungersb{\"o}ck and Sandra Richter and Lee Collier and Markus Mitterhauser and Georgios Karanikas and Rupert Lanzenberger and Robert Dudczak and Wolfgang Wadsak},
  journal={Nuclear medicine and biology},
  year={2012},
  volume={39 7},
  pages={
          1087-92
        }
}
INTRODUCTION Our aim was the optimization of radiochemical parameters for the microfluidic preparation of [(18)F]altanserin. The four main parameters evaluated were (1) precursor concentration, (2) reaction temperature, (3) bolus flow rate through the microreactor and (4) bolus volume. METHODS For the determination of optimal reaction conditions within a flow-through microreactor synthesizer, 5-400 μL of precursor and dried [(18)F]fluoride solution were simultaneously pushed through the… CONTINUE READING

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