Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials.

@article{Hou2005RadiolabeledCD,
  title={Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials.},
  author={Dongming Hou and Eyas Al-Shaykh Youssef and Todd J. Brinton and Ping Zhang and Pamela I. Rogers and Erik T. Price and Alan C. Yeung and Brian H. Johnstone and Paul G. Yock and Keith L. March},
  journal={Circulation},
  year={2005},
  volume={112 9 Suppl},
  pages={
          I150-6
        }
}
BACKGROUND Several clinical studies are evaluating the therapeutic potential of delivery of various progenitor cells for treatment of injured hearts. However, the actual fate of delivered cells has not been thoroughly assessed for any cell type. We evaluated the short-term fate of peripheral blood mononuclear cells (PBMNCs) after intramyocardial (IM), intracoronary (IC), and interstitial retrograde coronary venous (IRV) delivery in an ischemic swine model. METHODS AND RESULTS Myocardial… CONTINUE READING

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