Radiolabeled block copolymer micelles for image-guided drug delivery.

Abstract

We aimed at exploring block copolymer micelles (BCMs) for the simultaneous delivery of radiation/chemotherapy to cancer cells. To achieve that goal, we have prepared and characterized a novel type of docetaxel (DTX) loaded and non-loaded BCMs. The micelles were decorated with pyrazolyl-diamine chelating units to stabilize the matched pair 99mTc/Re for image… (More)
DOI: 10.1016/j.ijpharm.2016.11.004

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