Radiolabeled amino acids: basic aspects and clinical applications in oncology.

  title={Radiolabeled amino acids: basic aspects and clinical applications in oncology.},
  author={P. L. Jager and Willem Vaalburg and Jan Pruim and Elisabeth G. E. de Vries and Karl-Josef Langen and D. Albertus Piers},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={42 3},
As the applications of metabolic imaging are expanding, radiolabeled amino acids may gain increased clinical interest. This review first describes the basic aspects of amino acid metabolism, then continues with basic aspects of radiolabeled amino acids, and finally describes clinical applications, with an emphasis on diagnostic value. A special focus is on (11)C-methionine, (11)C-tyrosine, and (123)I-iodomethyltyrosine, because these have been most used clinically, although their common… CONTINUE READING
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