Radioiodine ablation of thyroid remnants after preparation with recombinant human thyrotropin in differentiated thyroid carcinoma: results of an international, randomized, controlled study.

@article{Pacini2006RadioiodineAO,
  title={Radioiodine ablation of thyroid remnants after preparation with recombinant human thyrotropin in differentiated thyroid carcinoma: results of an international, randomized, controlled study.},
  author={F. Pacini and P. Ladenson and M. Schlumberger and A. Driedger and M. Luster and R. Kloos and S. Sherman and B. Haugen and C. Corone and E. Molinaro and R. Elisei and C. Ceccarelli and A. Pinchera and R. Wahl and S. Leboulleux and M. Ricard and J. Yoo and N. Busaidy and E. Delpassand and H. Hanscheid and R. Felbinger and M. Lassmann and C. Reiners},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 3},
  pages={
          926-32
        }
}
CONTEXT After surgery for differentiated thyroid carcinoma, many patients are treated with radioiodine to ablate remnant thyroid tissue. This procedure has been performed with the patient in the hypothyroid state to promote endogenous TSH stimulation and is often associated with hypothyroid symptoms and impaired quality of life. OBJECTIVE AND INTERVENTION: This international, randomized, controlled, multicenter trial aimed to compare the efficacy and safety of recombinant human TSH (rhTSH) to… Expand
399 Citations

Paper Mentions

Interventional Clinical Trial
The purpose of this study is to determine [for patients with previously treated well-differentiated thyroid cancer and evidence of residual disease based on serum thyroglobulin… Expand
ConditionsThyroid Cancer
InterventionDrug
Adjuvant treatment with thyrotropin alpha for remnant ablation in thyroid cancer
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Preparation with Recombinant Human Thyroid-Stimulating Hormone for Thyroid Remnant Ablation with 131I Is Associated with Lowered Radiotoxicity
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Recombinant Human Thyroid Stimulating Hormone in Thyroid Remnant Ablation With 1.1 GBq 131Iodine in Low-Risk Patients
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A retrospective review of the effectiveness of recombinant human TSH as a preparation for radioiodine thyroid remnant ablation.
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Is diagnostic iodine-131 scanning with recombinant human TSH useful in the follow-up of differentiated thyroid cancer after thyroid ablation?
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