Radioimmunoscintigraphy of gastric adenocarcinomas with 99mTc-chimeric ccM4 antibody.

  title={Radioimmunoscintigraphy of gastric adenocarcinomas with 99mTc-chimeric ccM4 antibody.},
  author={Yi Zhang and Qing-wen Ma and Jie-cheng Zhao and Fangfei Gao and Shixi Liu and Qingshui Wang and Yue Chen and Jian-hai Xiang},
  journal={Cancer biotherapy & radiopharmaceuticals},
  volume={11 2},
Fourteen patients with gastric lesions were studied for radioimmunoscintigraphy using the 99mTc-ccM4 chimeric antibody reactive with the human tumor-associated TAG72 antigen. These include 10 gastric adenocarcinomas, 3 gastric ulcers and 1 gastric lymphoma. Each patient received an infusion of 30-40 mCi 99mTc-ccM4 antibody. Gamma camera scans were performed at 12-h postadministration. All patients underwent operation after radioimmunoscintigraphy. All surgical specimens including gastric… CONTINUE READING