Radioimmunoguided breast surgery using radiolabeled antibody NR-LU-10 FAB: a pilot study.

@article{Burak2001RadioimmunoguidedBS,
  title={Radioimmunoguided breast surgery using radiolabeled antibody NR-LU-10 FAB: a pilot study.},
  author={William E. Burak and Laura DePalatis and J L Mosic and D Soble and George Hinkle and Charles L. Hitchcock},
  journal={Tumori},
  year={2001},
  volume={87 3},
  pages={142-6}
}
AIM AND BACKGROUND Radioimmunoguided surgery using radiolabeled NR-LU-10 Fab was evaluated as a method of intraoperative breast cancer detection. METHODS Breast cancer patients were injected intravenously with 125I (74 MBq) labeled NR-LU-10 Fab (5 mg) and then underwent tumor excision 2, 4 or 7 days later, during which time the gamma detector probe was used to evaluate the primary tumor for evidence of radioactive uptake. RESULTS Intraoperative probing revealed tumor localization in 7 of 10… CONTINUE READING

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