Radioimmunoassay of Human Plasma Thyrotropin.

@article{Utiger1965RadioimmunoassayOH,
  title={Radioimmunoassay of Human Plasma Thyrotropin.},
  author={Robert D. Utiger},
  journal={The Journal of clinical investigation},
  year={1965},
  volume={44},
  pages={1277-86}
}
Many pituitary hormones possess partial or complete immunological species specificity. Earlier reports suggested that thyrotropin (TSH) did not have such specificity since the biological activity of human pituitary or plasma TSH could be neutralized by antisera to bovine TSH in doses similar to that which blocked the biological activity of bovine TSH (2, 3). However, recent studies have shown that much smaller doses of antisera to bovine or human TSH were able to neutralize the biological… CONTINUE READING

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